COLD STORAGE OF HUMAN PRECISION-CUT LUNG SLICES IN TIPROTEC PRESERVES CELLULAR COMPOSITION AND TRANSCRIPTIONAL RESPONSES AND ENABLES ON-DEMAND MECHANISTIC STUDIES

Abstract Background Human precision-cut lung slices (hPCLS) are a unique platform for functional, mechanistic, and drug discovery studies in the field of respiratory research.However, tissue availability, generation, and cultivation time represent important challenges for their usage.Therefore, the present study evaluated the efficacy of a specific

Abstract Efficient and safe cell engineering by transfection of nucleic acids remains one of the long-standing hurdles for fundamental biomedical research and many new therapeutic applications, such as CAR T HERBATINT 8N cell-based therapies.mRNA has recently gained increasing attention as a more safe and versatile alternative tool over viral- or D

This paper reports on an experimental animal study evaluating a method of mandibular reconstruction in dogs using autogenous corticocaneclous bone graft and fibrin glue.Eight animals underwent a resection at the mandibular body and primary reconstruction was carried out using osteosynthesis plates and screws.The defect was bridged with an autogenou

Journalistic photos appear in newspapers for news purposes.In many cases, many parties are interested in using Mittens the mass media for their own vested interests.The photos of the Presidential and Vice-Presidential candidates in the 2009 Indonesian election were examples of such uses.These photos contained symbols which were manipulated and pres

Brief episodes of low oxygen breathing (therapeutic acute intermittent hypoxia; tAIH) may serve as an effective plasticity-promoting primer to enhance the effects of transcutaneous spinal stimulation-enhanced walking therapy (WALKtSTIM) in persons with chronic (>1 year) spinal cord injury (SCI).Pre-clinical studies in rodents with SCI show that